Clinical Studies of Induction Agents. Vi. Miscellaneous Observations with G.29.505.

Using G.29.505 the incidence of excitatory phenomena occurring after premedication with atropine and opiate was insignificantly different from that after atropine alone, whereas after hyoscine it was three times as high. Respiratory disturbances were significantly less frequent when an opiate was used with atropine than after atropine or hyoscine alone. G.29.505 was compared with nitrous oxide and oxygen for use in minor procedures. It did not prolong the time required, but was followed by a much higher incidence of brief but troublesome restlessness. Vein damage was much more frequent than after methohexitone or thiopentone.